What is a potential complication associated with polycythemia vera?

Polycythemia vera is a myeloproliferative disorder characterized by an overproduction of red blood cells, which can lead to increased blood viscosity. This increased viscosity can elevate the likelihood of thrombosis, or clot formation, due to sluggish blood flow and altered hemodynamics. Patients with polycythemia vera often experience complications that arise from this heightened risk of clotting, which can manifest as thromboembolic events such as deep vein thrombosis, pulmonary embolism, or cerebrovascular accidents (strokes).

The overproduction of red blood cells can also affect platelets and white blood cells, contributing to an increased overall clotting tendency. The management of polycythemia vera often involves monitoring blood counts and may include therapeutic phlebotomy or medication to reduce the risk of clotting.

Other options presented may appear relevant but do not align with the primary complications associated with polycythemia vera. For instance, increased risk of bleeding is typically not a hallmark of this condition; rather, patients might have a paradoxical increased risk of clotting due to the effects of the disease. Anemia is generally more characteristic of other types of conditions or treatments, such as those involving bone marrow suppression. Muscle wasting is not specifically associated