What class of medication is commonly prescribed to address isolated systolic hypertension?

Isolated systolic hypertension, characterized by an elevated systolic blood pressure while the diastolic remains normal, is particularly common in older adults. Calcium channel blockers are widely used for treating this condition due to their ability to effectively lower systolic blood pressure. They work by inhibiting calcium influx into vascular smooth muscle and cardiac muscle cells, leading to vasodilation and decreased myocardial contractility. This dual action helps reduce both systolic and diastolic blood pressure, but their impact on systolic readings is especially notable.

Furthermore, calcium channel blockers are often well-tolerated and have a favorable side effect profile, making them particularly appropriate for managing isolated systolic hypertension in the aging population. While other medication classes can also be utilized to manage hypertension, their mechanisms may not be as effective specifically for isolated systolic hypertension, especially among older patients. This is why calcium channel blockers are a preferred choice in such clinical scenarios.